Proteoglycan fragments in joint fluid

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منابع مشابه

Measurement of sulphated glycosaminoglycans and proteoglycan fragments in arthritic synovial fluid.

Immunoreactive proteoglycans (iPGs) and sulphated glycosaminoglycans (GAGs) were assayed in synovial fluid obtained from 22 patients with osteoarthritis (OA), 21 with rheumatoid arthritis (RA), 13 with gout, and five with Reiter's syndrome. A strong positive linear correlation was observed between concentrations of sulphated GAGs and iPGs in RA (r = 0.95) and gout (r = 0.94). A linear correlati...

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Clearance of proteoglycan from joint cavities.

The rate of loss from the synovial cavity of proteoglycan subunit, a major constituent of cartilage, has been measured in rabbits with and without experimental arthritis. The effect of aggregation between proteoglycan and hyaluronic acid upon the rate of elimination has also been investigated. The results indicate that proteoglycan subunit has a clearance half life of around 12 hours in normal ...

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Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.

OBJECTIVE To identify the major aggrecanase- and matrix metalloproteinase (MMP)-generated aggrecan fragments in human osteoarthritis (OA) synovial fluid and in human OA joint cartilage. METHOD Aggrecan fragments were prepared by CsCl gradient centrifugation. Fragment distributions were compared with aggrecanase-1 (ADAMTS-4) and MMP-3 digested human aggrecan by analysis with neoepitope antibod...

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Synovial fluid-derived synovial fragments represent an improved source of synovial mesenchymal stem cells in the temporomandibular joint

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Joint fluid pressure in chronic knee effusions.

With sterile precautions and after infiltration with local anaesthetic, a special type of needle was introduced into the lateral aspect of the knee near the upper border of the patella. This needle (S.W.G. 18, Down Bros., with a short bevel and perforations made in the sides 0 5 cm. from the point to prevent blockage) had a tap and a side-arm. A manometer filled with normal saline was attached ...

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ژورنال

عنوان ژورنال: Acta Orthopaedica Scandinavica

سال: 1992

ISSN: 0001-6470

DOI: 10.3109/17453679209154758